[D-Pro2, D-Phe7, D-Trp9] Substance P
[D-Pro2, D-Phe7, D-Trp9] Substance P is a Substance P analogue. [D-Pro2, D-Phe7, D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2, D-Phe7, D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly[1][2].
Product Specifications
CAS Number
77275-70-8
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-pro2-d-phe7-d-trp9-substance-p.html
Solubility
H2O
Smiles
O=C([C@H]1N(CCC1)C([C@H](CCCCN)NC([C@@H]2N(CCC2)C([C@@H](N)CCCNC(N)=N)=O)=O)=O)N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O
Molecular Formula
C72H105N19O13S
Molecular Weight
1476.79
References & Citations
[1]Hawcock AB, et al. Agonist effects of [D-Pro2, D-Phe7, D-Trp9]substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80 (1) :135-8.|[2]Folkers K, et al. Chemical design of antagonists of substance P. Acta Physiol Scand. 1981 Apr;111 (4) :505-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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