Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Isoxanthohumol

Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases[1][2][3][4][5].

Product Specifications

CAS Number

521-48-2

UNSPSC

12352005

Target

Apoptosis; Autophagy; CMV; Fungal; HSV; Integrin; Reactive Oxygen Species (ROS) ; S100 Protein

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isoxanthohumol.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC(OC)=C2C(CC(OC2=C1C/C=C(C)\C)C3=CC=C(C=C3)O)=O

Molecular Formula

C21H22O5

Molecular Weight

354.40

References & Citations

[1]Żołnierczyk AK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82.|[2]Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268.|[3]Yan YF, et al. The Antifungal Mechanism of Isoxanthohumol from Humulus lupulus Linn. Int J Mol Sci. 2021 Oct 7;22 (19) :10853.|[4]Yang JY, et al. Effect of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis. Apoptosis. 2007 Nov;12 (11) :1953-63.|[5]Yang YN, et al. Therapeutic effects and mechanisms of isoxanthohumol on DSS-induced colitis: regulating T cell development, restoring gut microbiota, and improving metabolic disorders. Inflammopharmacology. 2024 Jun;32 (3) :1983-1998.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ABT 199 (>99%)(Venetoclax)
TRC-A112425-10MG 10 mg

ABT 199 (>99%)(Venetoclax)

Sign In for Pricing
View Details
Met Mouse Gene Knockout Kit (CRISPR)
KN309983 1 Kit

Met Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
PSMG3 (NM_001134340) Human Over-expression Lysate
LC427395 20 µg

PSMG3 (NM_001134340) Human Over-expression Lysate

Sign In for Pricing
View Details
Smim7 (NM_172396) Mouse Tagged ORF Clone
MG200099 10 µg

Smim7 (NM_172396) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
KCNJ5 (NM_000890) Human Over-expression Lysate
LY424464 100 µg

KCNJ5 (NM_000890) Human Over-expression Lysate

Sign In for Pricing
View Details
MARK2 (C-term) Rabbit Polyclonal Antibody
AP14909PU-N 400 µL

MARK2 (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details