DBCO-NHS ester 2
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC) . DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
[1384870-47-6]
Product Name Alternative
PQQ; Methoxatin
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhs-ester-2.html
Purity
99.69
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Smiles
O=C1CCC(N1OC(CCCCC(N2C3=CC=CC=C3C#CC(C=CC=C4)=C4C2)=O)=O)=O
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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