STX-0119
Product Specifications
UNSPSC Description
STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM[1].
Target Antigen
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stx-0119.html
Purity
99.21
Solubility
DMSO : 13.33 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=CC(C2=CC=CC=C2)=NC3=C1C=CC=C3)NC4=NN=C(C5=CC=CO5)O4
Molecular Weight
382.37
References & Citations
[1]Matsuno K, et al. Identification of a New Series of STAT3 Inhibitors by Virtual Screening. ACS Med Chem Lett. 2010 Jul 13;1(8):371-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103692/STX-0119-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103692/STX-0119-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
851095-32-4
Available Sizes
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