LY334370

LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM.

Product Specifications

CAS Number

[182563-08-2]

UNSPSC

12352005

Hazard Statement

H317, H319

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/LY334370.html

Purity

99.73

Solubility

DMSO : ≥ 55.5 mg/mL

Smiles

O=C(C1=CC=C(F)C=C1)NC2=CC3=C(C=C2)NC=C3C4CCN(C)CC4

Molecular Formula

C21H22FN3O

Molecular Weight

351.42

Precautions

H317, H319

References & Citations

[1]Shepheard S, et al. Possible antimigraine mechanisms of action of the 5HT1F receptor agonist LY334370. Cephalalgia. 1999 Dec;19 (10) :851-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

5-HT1 Receptor; mLAG-3

Available Sizes

Curated Selection

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