LY334370
LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM.
Product Specifications
CAS Number
[182563-08-2]
UNSPSC
12352005
Hazard Statement
H317, H319
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/LY334370.html
Purity
99.73
Solubility
DMSO : ≥ 55.5 mg/mL
Smiles
O=C(C1=CC=C(F)C=C1)NC2=CC3=C(C=C2)NC=C3C4CCN(C)CC4
Molecular Formula
C21H22FN3O
Molecular Weight
351.42
Precautions
H317, H319
References & Citations
[1]Shepheard S, et al. Possible antimigraine mechanisms of action of the 5HT1F receptor agonist LY334370. Cephalalgia. 1999 Dec;19 (10) :851-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor; mLAG-3
Available Sizes
Curated Selection
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