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IL-17A modulator-1

IL-17A modulator-1 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 9. IL-17A modulator-1 inhibits the biological action of IL-17A with a pIC50 of 8.2. IL-17A modulator-1 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders[1].

Product Specifications

CAS Number

[2748749-29-1]

UNSPSC

12352005

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/il-17a-modulator-1.html

Purity

98.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=NN1C)N[C@H](C(NC2=CC=C(C3=C(OC)C=NC=C3OC)C=C2)=O)C(C4=CC=CC=C4)C5=CC=CC=C5

Molecular Formula

C33H31N5O4

Molecular Weight

561.63

References & Citations

[1]Barrie Phillip MARTIN, et al. Preparation of amino acid amides as IL-17A modulators. WO2021239743 A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IL-17

Available Sizes

Curated Selection

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