Imidazole ketone erastin
Product Specifications
UNSPSC Description
Imidazole ketone erastin is a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system xc- and an activator of ferroptosis. Imidazole ketone erastin has anti-tumor activity[1].
Target Antigen
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Imidazole_ketone_erastin.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC(C(CN3C=CN=C3)=O)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=CC=CC=C61
Molecular Weight
655.14
References & Citations
[1]Zhang Y, et al. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. Cell Chem Biol. 2019 Jan 31. pii: S2451-9456(19)30030-3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114481/Imidazole-ketone-erastin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114481/Imidazole-ketone-erastin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1801530-11-9
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Galectin-9 Antibody (9M1-3) [Alexa Fluor 350]](https://cdn.genprice.uk/genprice/genprice5.png)
NBP3-18530AF350 0.1 mL
Mouse Monoclonal Galectin-9 Antibody (9M1-3) [Alexa Fluor 350]
Ask
View Details 
