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RS-104966

RS-104966 is a potent collagenase-1 (MMP-1) inhibitor. RS-104966 induces a conformational change in the side chains of the S10 pocket of MMP-1[1].

Product Specifications

CAS Number

[193022-38-7]

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rs-104966.html

Purity

98.39

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NO)CC1(S(=O)(C2=CC=C(OC3=CC=CC=C3)C=C2)=O)CCOCC1

Molecular Formula

C19H21NO6S

Molecular Weight

391.44

References & Citations

[1]Källblad P, et al. Efficient conformational sampling of local side-chain flexibility. J Mol Biol. 2003 Mar 7;326 (5) :1651-65.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MMP-1

Available Sizes

Curated Selection

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