ECPLA
ECPLA, a lysergamide lysergic acid diethylamidean (LSD) analog, is a potent 5-HT2A agonist (EC50 of 14.6 nM) for Gq-mediated calcium flux. ECPLA has high affinity for most serotonin receptors, α2-adrenoceptors, and D2-like dopamine receptors[1].
Product Specifications
CAS Number
2349367-50-4
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ecpla.html
Smiles
CN1[C@@]2([H])C(C3=CC=CC4=C3C(C2)=CN4)=C[C@H](C1)C(N(C5CC5)CC)=O
Molecular Formula
C21H25N3O
Molecular Weight
335.44
References & Citations
[1]Adam L Halberstadt, et al. Pharmacological characterization of the LSD analog N-ethyl-N-cyclopropyl lysergamide (ECPLA) . Psychopharmacology (Berl) . 2019 Feb;236 (2) :799-808.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
Available Sizes
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