(2S,3R) -DEPMPO-Biotin
(2S,3R) -DEPMPO-Biotin is a spin trapping agent consists of DEPMPO (HY-120976) and Biotin (HY-B0511) . (2S,3R) -DEPMPO-Biotin captures macromolecule free radicals in lesions[1].
Product Specifications
CAS Number
[936224-52-1]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2s-3r-depmpo-biotin.html
Solubility
10 mM in DMSO
Smiles
O=C(OC[C@@H]1[C@](C)(P(OCC)(OCC)=O)[N+]([O-])=CC1)NCCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O
Molecular Formula
C24H42N5O8PS
Molecular Weight
591.66
References & Citations
[1]Liu H, et al. In vivo Detection of Macromolecule Free Radicals in Mouse Sepsis-Associated Encephalopathy Using a New MRI and Immunospin Trapping Strategy. Int J Nanomedicine. 2022 Sep 1;17:3809-3820.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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