(2S,3R) -DEPMPO-Biotin

(2S,3R) -DEPMPO-Biotin is a spin trapping agent consists of DEPMPO (HY-120976) and Biotin (HY-B0511) . (2S,3R) -DEPMPO-Biotin captures macromolecule free radicals in lesions[1].

Product Specifications

CAS Number

[936224-52-1]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2s-3r-depmpo-biotin.html

Solubility

10 mM in DMSO

Smiles

O=C(OC[C@@H]1[C@](C)(P(OCC)(OCC)=O)[N+]([O-])=CC1)NCCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O

Molecular Formula

C24H42N5O8PS

Molecular Weight

591.66

References & Citations

[1]Liu H, et al. In vivo Detection of Macromolecule Free Radicals in Mouse Sepsis-Associated Encephalopathy Using a New MRI and Immunospin Trapping Strategy. Int J Nanomedicine. 2022 Sep 1;17:3809-3820.