Fmoc-Ala-Ala-PAB
Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
1384263-83-5
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-ala-ala-pab.html
Purity
98.86
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O
Molecular Formula
C28H29N3O5
Molecular Weight
487.55
References & Citations
[1]Wayne C Widdison, et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing. Bioconjug Chem. 2015 Nov 18;26 (11) :2261-78.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PDEM100161-01 20 µg
Recombinant Mouse Lymphotoxin-α/TNF-β Protein (Sumo Tag)
Sign In for Pricing
View Details PDEM100161-02 100 µg
Recombinant Mouse Lymphotoxin-α/TNF-β Protein (Sumo Tag)
Sign In for Pricing
View Details PDEM100161-03 500 µg
Recombinant Mouse Lymphotoxin-α/TNF-β Protein (Sumo Tag)
Sign In for Pricing
View Details PDEM100161-04 1 mg
Recombinant Mouse Lymphotoxin-α/TNF-β Protein (Sumo Tag)
Sign In for Pricing
View Details 
