Cyclotriazadisulfonamide (hydrochloride)
Cyclotriazadisulfonamide (CADA) hydrochloride is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the cell surface, effectively inhibiting HIV transmission. Cyclotriazadisulfonamide hydrochloride can inhibit HIV-1 (NL4.3) and SIV (mac251), and has a synergistic effect when used in combination with cellulose acetate (CAP) . Cyclotriazadisulfonamide hydrochloride can also be used as a microbial gel formulation to maintain CD4 downregulation and antiviral activity, and is a broad-spectrum anti-HIV agent.
Product Specifications
CAS Number
392287-03-5
Product Name Alternative
CADA (hydrochloride)
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyclotriazadisulfonamide-hydrochloride.html
Smiles
O=S(C1=CC=C(C)C=C1)(N2CC(CN(S(=O)(C3=CC=C(C)C=C3)=O)CCCN(CCC2)CC4=CC=CC=C4)=C)=O.Cl
Molecular Formula
C31H40ClN3O4S2
Molecular Weight
618.25
References & Citations
[1]CADA, a potential anti-HIV microbicide that specifically targets the cellular CD4 receptor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Tyrosinase (T311), CF488A conjugate, 0.1mg/mL
Human IgG Immunoglobulin (IG266), CF568 conjugate, 0.1mg/mL
Myosin, Smooth Muscle Heavy Chain (MYH11/923), CF647 conjugate, 0.1mg/mL
ZAP70 (ZAP70/528), CF568 conjugate, 0.1mg/mL
