Sulfadiazine (sodium)

Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research[1][2].

Product Specifications

CAS Number

[547-32-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Antibiotic; Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sulfadiazine-sodium.html

Purity

98.0

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C1=CC=C(N)C=C1)(N([Na])C2=NC=CC=N2)=O

Molecular Formula

C10H9N4NaO2S

Molecular Weight

272.26

Precautions

H302, H315, H319

References & Citations

[1]Kopmann C, et al. Abundance and transferability of antibiotic resistance as related to the fate of sulfadiazine in maize rhizosphere and bulk soil. FEMS Microbiol Ecol. 2013 Jan;83 (1) :125-34.|[2]Silva LA, et al. Efficacy of sulfadiazine and pyrimetamine for treatment of experimental toxoplasmosis with strains obtained from human cases of congenital disease in Brazil. Exp Parasitol. 2019 Jul;202:7-14.