Mafenide (hydrochloride)

Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].

Product Specifications

CAS Number

[138-37-4]

UNSPSC

12352005

Hazard Statement

H317

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Mafenide-hydrochloride.html

Purity

99.97

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(CN)C=C1)(N)=O.[H]Cl

Molecular Formula

C7H11ClN2O2S

Molecular Weight

222.70

Precautions

H317

References & Citations

[1]Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284 (23) : p. 1324.|[2]Ashkan Afshari, et al. The Effective Duration of Antimicrobial Activity of Mafenide Acetate After Reconstitution. J Burn Care Res. 2018 Aug 17;39 (5) :736-738.