AChE-IN-26

AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor with an IC50 value of 0.42 μM. AChE-IN-26 can be used for the research of Alzheimer’s disease[1].

Product Specifications

CAS Number

[2977170-10-6]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-26.html

Purity

99.73

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=[N+](CC2=CC=CC=C2)C=C1)C3=CC=C(OC)C(OC)=C3.[Br-]

Molecular Formula

C21H21BrN2O3

Molecular Weight

429.31

References & Citations

[1]Abdullaha M, et al. Discovery of methoxy-naphthyl linked N- (1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. Eur J Med Chem. 2020 Dec 1;207:112761.