Heparin (sodium salt)

Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions.

Product Specifications

CAS Number

[9041-08-1]

Product Name Alternative

Sodium heparin; Sodium heparinate

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Autophagy; Factor Xa; Thrombin

Type

Reference compound

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Heparin-sodium-salt.html

Purity

98.00

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H](O[C@H]2[C@H](OS(O)(=O)=O)[C@@H](O)[C@H](OC)[C@H](C(O)=O)O2)[C@@H](COS(O)(=O)=O)O[C@H](OC)[C@@H]1NS(O)(=O)=O.[n].[.xNa]

Molecular Formula

(C14H25NO20S3) n.xNa

Molecular Weight

6117(Average)

Precautions

H315, H319, H335

References & Citations

[1]Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41 (3) :391-412.|[2]Anurag Purushothaman, et al. Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. J Biol Chem. 2016 Jan 22;291 (4) :1652-63.