Favipiravir
Product Specifications
UNSPSC Description
Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC50 of 341 nM.
Target Antigen
Bacterial; DNA/RNA Synthesis; Influenza Virus; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/T_705.html
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 6.25 mg/mL (ultrasonic)
Smiles
O=C(N)C1=NC(F)=CNC1=O
Molecular Weight
157.10
References & Citations
[1]Furuta Y, et al. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013 Nov;100(2):446-54.|[2]Rocha-Pereira J, et al. Favipiravir (T-705) inhibits in vitro norovirus replication.
 Biochem Biophys Res Commun. 2012 Aug 10;424(4):777-80.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14768/Favipiravir-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14768/Favipiravir-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
259793-96-9
Available Sizes
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