Valpromide
Valpromide is an amide derivative of Valproic acid and an orally active epoxide hydrolase inhibitor that can cross the blood-brain barrier. Valpromide has antiepileptic, anticonvulsant, and antipsychotic effects. Valpromide also exhibits antiviral activity and can inhibit the reactivation of the EBV lytic cycle[1][2][3][4].
Product Specifications
CAS Number
2430-27-5
UNSPSC
12352211
Hazard Statement
H302
Target
EBV; Epoxide Hydrolase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Valpromide.html
Purity
99.72
Solubility
DMSO : ≥ 50 mg/mL
Smiles
CCCC(CCC)C(N)=O
Molecular Formula
C8H17NO
Molecular Weight
143.23
Precautions
H302
References & Citations
[1]Pacifici GM, et al. Valpromide inhibits human epoxide hydrolase. Br J Clin Pharmacol. 1986 Sep;22 (3) :269-74.|[2]Gorres KL, et al. Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus. MBio. 2016 Mar 1;7 (2) :e00113.|[3]Radatz M, et al. Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid. Epilepsy Res. 1998 Mar;30 (1) :41-8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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