Fmoc-NH-ethyl-SS-propionic acid
Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
864235-83-6
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-nh-ethyl-ss-propionic-acid.html
Purity
99.53
Solubility
DMSO : 29.17 mg/mL (ultrasonic)
Smiles
O=C(O)CCSSCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Molecular Formula
C20H21NO4S2
Molecular Weight
403.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD100 (Semaphorin-4D) (A8), CF640R conjugate, 0.1mg/mL
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
CD45RO (190-2F2.5), CF740 conjugate, 0.1mg/mL
Mucin 5AC (MUC5AC) (58M1), CF568 conjugate, 0.1mg/mL
