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Isolithocholic acid

Selected Variant

HY-B0172B-01

Size: 5 mg

Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2].

Product Specifications

CAS Number

1534-35-6

Product Name Alternative

3β-Hydroxy-5β-cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/isolithocholic-acid.html

Purity

99.78

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@H](CC4)O)([H])CC3)C

Molecular Formula

C24H40O3

Molecular Weight

376.57

References & Citations

[1]Batta AK, et al. Transformation of bile acids into iso-bile acids by Clostridium perfringens: possible transport of 3 beta-hydrogen via the coenzyme. Hepatology. 1985;5 (6) :1126-1131.|[2]Borriello SP, et al. The metabolism of lithocholic acid and lithocholic acid-3-alpha-sulfate by human fecal bacteria. Lipids. 1982;17 (7) :477-482.|[3]Thanissery R, et al. Inhibition of spore germination, growth, and toxin activity of clinically relevant C. difficile strains by gut microbiota derived secondary bile acids. Anaerobe. 2017;45:86-100.|[4]Lin H, et al. Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model. J Agric Food Chem. 2019;67 (13) :3624-3632.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Microbial Metabolite

Available Sizes

Price

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