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2,6-Dichloropurine

2,6-Dichloropurine is a pharmaceutical intermediate. 2,6-Dichloropurine can be used to synthesize various PDE inhibitors, human A3 adenosine receptor (AR) antagonists, and CDK inhibitors[1][2][3].

Product Specifications

CAS Number

5451-40-1

UNSPSC

12352200

Hazard Statement

H301

Target

Drug Intermediate

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-6-dichloropurine.html

Purity

99.95

Solubility

DMSO : ≥ 200 mg/mL

Smiles

C2=NC1=C(C(=NC(=N1)Cl)Cl)[NH]2

Molecular Formula

C5H2Cl2N4

Molecular Weight

189.00

Precautions

H301

References & Citations

[1]Kozai S, et al. Synthesis and biological activity of 9- (2, 6-difluorobenzyl) -9H-purines bearing chlorine. Chemical and pharmaceutical bulletin, 1999, 47 (4) : 574-575.|[2]Jeong LS, et al. Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4'-thioadenosine derivatives without 4'-hydroxymethyl group as highly potent and selective antagonists. J Med Chem. 2007 Jul 12;50 (14) :3159-62.|[3]Oumata N, et al. Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1. J Med Chem. 2008 Sep 11;51 (17) :5229-42.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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