4-Nitrophenyl β-D-glucuronide

4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-Nitrophenol. 4-Nitrophenyl β-D-glucuronide is the chromogenic substrate for β-glucuronidase[1].

Product Specifications

CAS Number

[10344-94-2]

Product Name Alternative

PNPG_1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

β-glucuronidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-nitrophenyl-β-d-glucuronide.html

Purity

99.13

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC=C(C=C2)[N+]([O-])=O)=O

Molecular Formula

C12H13NO9

Molecular Weight

315.23

Precautions

H302, H315, H319, H335

References & Citations

[1]A Mariscal, et al. Interference by carbohydrate substrates, flavonoids, and monosaccharide derivatives on bacterial beta-D-glucuronidase assays. Arch Environ Contam Toxicol. 1998 Nov;35 (4) :588-93. |[2]Andersen B. Quantification of Escherichia coli via Analysis of β-glucuronidase Enzyme Concentrations[J]. Student Research Proceedings, 2017, 2 (1) .