BAY-6096
BAY-6096, a chemical probe, is a potent, selective, and highly water-soluble adrenergic receptor α2B antagonist with an IC50 of 14 nM. BAY-6096 can effectively reduceα 2B receptor agonist-induced rat vascular contraction[1].
Product Specifications
CAS Number
[2313483-41-7]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bay-6096.html
Purity
98.07
Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC2=NC=C(C3=C(C)ON=C3C)N2C=C1)NCC[N+]4=CC=C(NC)C=C4.[Cl-]
Molecular Formula
C21H23ClN6O2
Molecular Weight
426.90
References & Citations
[1]Meibom D, et al. BAY-6096: A Potent, Selective, and Highly Water-Soluble Adrenergic α2B Antagonist. J Med Chem. 2023 Apr 13;66 (7) :4659-4670.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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