Foxy-5
Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2][3].
Product Specifications
CAS Number
881188-51-8
UNSPSC
12352209
Target
Wnt
Type
Peptides
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/foxy-5.html
Purity
99.56
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@@H](NC=O)CCSC)=O)=O)=O)N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)CC(C)C)=O
Molecular Formula
C26H42N6O12S2
Molecular Weight
694.77
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
Phase 2
Isoform
Wnt5
Citation 01
Available Sizes
Frequently Asked Questions
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