NCGC00262650
NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells with an IC50 of 9.8 μM[1].
Product Specifications
CAS Number
344359-25-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ncgc00262650.html
Purity
99.22
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC1=C2C(N(C3CCCC3)C=C2C4=CC=C(OC)C=C4)=NC=N1
Molecular Formula
C18H20N4O
Molecular Weight
308.38
Precautions
H302, H315, H319
References & Citations
[1]Srinivasan P, et, al. Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion. Nat Commun. 2013;4:2261.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400276-100 1x 100 µL
TAG-72 / CA72.4 (B72.3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680181-500 1x 500 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details