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VU0240382

VU0240382 is a metabotropic glutamate receptor subtype 5 modulator whose activity differs depending on whether it has allosteric agonist activity. VU0240382 with allosteric agonist activity can activate mGlu (5) receptors in cell lines, but has no agonist activity in natural systems and has similar efficacy to mGlu (5) modulators without allosteric agonist activity in animal models.

Product Specifications

CAS Number

1092550-36-1

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/vu0240382.html

Smiles

O=C1NCCC2=C1C=CC(C#CC3=CC=CC=C3)=C2

Molecular Formula

C17H13NO

Molecular Weight

247.29

References & Citations

[1]Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system function

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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