PROTAC SMARCA2 degrader-30
PROTAC SMARCA2 degrader-30 (example 85) is a PROTAC SMARCA2 degrader with a DC50 less than 100 nM in H1299 cells[1].
Product Specifications
CAS Number
[2408393-67-7]
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-degrader-30.html
Smiles
O=C1NC(C(CC1)N2C3=NC=CC=C3C4=CC(CN5CCC(CC5)CN(CCN6CCN(CC6)CC7=CC=C(C8=CC(C9=C(O)C=CC=C9)=NN=C8N)C=C7)C)=CC=C42)=O
Molecular Formula
C47H54N10O3
Molecular Weight
807.00
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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