PROTAC SMARCA2 degrader-30

PROTAC SMARCA2 degrader-30 (example 85) is a PROTAC SMARCA2 degrader with a DC50 less than 100 nM in H1299 cells[1].

Product Specifications

CAS Number

[2408393-67-7]

UNSPSC

12352005

Target

Epigenetic Reader Domain; PROTACs

Type

Reference compound

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-smarca2-degrader-30.html

Smiles

O=C1NC(C(CC1)N2C3=NC=CC=C3C4=CC(CN5CCC(CC5)CN(CCN6CCN(CC6)CC7=CC=C(C8=CC(C9=C(O)C=CC=C9)=NN=C8N)C=C7)C)=CC=C42)=O

Molecular Formula

C47H54N10O3

Molecular Weight

807.00

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

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