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ALPK1-IN-2

Product Specifications

CAS Number

[2765633-68-7]

UNSPSC Description

ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM[1].

Target Antigen

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alpk1-in-2.html

Solubility

DMF : 50 mg/mL (ultrasonic)|DMSO : 50 mg/mL (ultrasonic)

Smiles

COC1=CC=CC2=C1N=C(S2)NC(C3=C(C=C(C=C3F)N4CC5CC(N5)C4)F)=O

Molecular Weight

416.44

References & Citations

[1]Danyang Liu, et al. Benzothiazole and quinoline derivatives and their use. WO2022063153A1.

Shipping Conditions

Room Temperature

Clinical Information

No Development Reported

Available Sizes

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