ALPK1-IN-2
Product Specifications
UNSPSC Description
ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM[1].
Target Antigen
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alpk1-in-2.html
Solubility
DMF : 50 mg/mL (ultrasonic)|DMSO : 50 mg/mL (ultrasonic)
Smiles
COC1=CC=CC2=C1N=C(S2)NC(C3=C(C=C(C=C3F)N4CC5CC(N5)C4)F)=O
Molecular Weight
416.44
References & Citations
[1]Danyang Liu, et al. Benzothiazole and quinoline derivatives and their use. WO2022063153A1.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147562/ALPK1-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147562/ALPK1-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2765633-68-7
Available Sizes
Curated Selection
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