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Valbenazine

Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1].

Product Specifications

Product Name Alternative

NBI-98854

UNSPSC

12352005

Hazard Statement

H301, H336, H373

Target

Monoamine Transporter

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Valbenazine.html

Purity

98.61

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C([C@@H](N)C(C)C)O[C@@H]1C[C@]2([H])C3=CC(OC)=C(OC)C=C3CCN2C[C@H]1CC(C)C

Molecular Formula

C24H38N2O4

Molecular Weight

418.57

Precautions

H301, H336, H373

References & Citations

[1]Dimitri E Grigoriadis, et al. Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites. J Pharmacol Exp Ther. 2017 Jun;361 (3) :454-461.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-16771/Valbenazine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-16771/Valbenazine-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Launched

CAS Number

[1025504-45-3]

Available Sizes

Curated Selection

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