Valbenazine
Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1].
Product Specifications
CAS Number
[1025504-45-3]
Product Name Alternative
NBI-98854
UNSPSC
12352005
Hazard Statement
H301, H336, H373
Target
Monoamine Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Valbenazine.html
Purity
98.61
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)C(C)C)O[C@@H]1C[C@]2([H])C3=CC(OC)=C(OC)C=C3CCN2C[C@H]1CC(C)C
Molecular Formula
C24H38N2O4
Molecular Weight
418.57
Precautions
H301, H336, H373
References & Citations
[1]Dimitri E Grigoriadis, et al. Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites. J Pharmacol Exp Ther. 2017 Jun;361 (3) :454-461.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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