MID-1
MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake[1].
Product Specifications
CAS Number
[312608-54-1]
Product Name Alternative
MLV-6976; NC-1209,MLV-6976 (hydrochloride); NC-1200 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Insulin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mid-1.html
Purity
99.36
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(OCC)C=C2
Molecular Formula
C12H11N3O4S
Molecular Weight
293.30
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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