MMPP

MMPP is an anti-inflammatory agent. MMPP prevents LPS-induced mortality by inhibiting the inflammatory response via STAT3 activity inhibition[1][2].

Product Specifications

CAS Number

[1895957-18-2]

Product Name Alternative

Ro 40-7591

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mmpp.html

Purity

99.31

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(C=C1OC)/C=C/CC2=CC=C(C=C2)OC

Molecular Formula

C17H18O3

Molecular Weight

270.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Son DJ, et, al. Novel synthetic (E) -2-methoxy-4- (3- (4-methoxyphenyl) prop-1-en-1-yl) phenol inhibits arthritis by targeting signal transducer and activator of transcription 3. Sci Rep. 2016 Nov 15:6:36852.|[2]Kim B, et, al. (E) -2-methoxy-4- (3- (4-methoxyphenyl) prop-1-en-1-yl) phenol alleviates inflammatory responses in LPS-induced mice liver sepsis through inhibition of STAT3 phosphorylation. Int Immunopharmacol. 2023 Dec;125 (Pt A) :111124.