Cetilistat
Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively[1].
Product Specifications
CAS Number
282526-98-1
Product Name Alternative
ATL-962
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Cetilistat.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL (ultrasonic) |Ethanol : 2.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
CC1=CC=C(N=C(OCCCCCCCCCCCCCCCC)OC2=O)C2=C1
Molecular Formula
C25H39NO3
Molecular Weight
401.58
Precautions
H302, H315, H319, H335
References & Citations
[1]Yamada Y, et al. Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats. Horm Metab Res. 2008 Aug;40 (8) :539-43.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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