Cetilistat

Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively[1].

Product Specifications

CAS Number

[282526-98-1]

Product Name Alternative

ATL-962

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Lipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Cetilistat.html

Purity

98.0

Solubility

DMSO : < 1 mg/mL (ultrasonic) |Ethanol : 2.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

CC1=CC=C(N=C(OCCCCCCCCCCCCCCCC)OC2=O)C2=C1

Molecular Formula

C25H39NO3

Molecular Weight

401.58

Precautions

H302, H315, H319, H335

References & Citations

[1]Yamada Y, et al. Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats. Horm Metab Res. 2008 Aug;40 (8) :539-43.