Mebendazole-amine

Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent[1].

Product Specifications

CAS Number

[52329-60-9]

Product Name Alternative

trans-4-Aminocrotonic acid

UNSPSC

12352005

Hazard Statement

H302

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mebendazole-amine.html

Purity

98.35

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C2N=C(N)NC2=C1)C3=CC=CC=C3

Molecular Formula

C14H11N3O

Molecular Weight

237.26

Precautions

H302

References & Citations

[1]Majewsky M, et al. Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS. J Pharm Biomed Anal. 2018;151:151-158.|[2]Pantziarka P, et al. Repurposing Drugs in Oncology (ReDO) -mebendazole as an anti-cancer agent. Ecancermedicalscience. 2014;8:443. Published 2014 Jul 10.