Atipamezole (hydrochloride)
Product Specifications
Product Name Alternative
MPV-1248 hydrochloride
UNSPSC Description
Atipamezole (MPV-1248) hydrochloride is a potent α2-adrenoceptor antagonist with a Ki of 1.6 nM[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Atipamezole-hydrochloride.html
Purity
99.97
Solubility
DMSO : ≥ 47 mg/mL|H2O : 75 mg/mL (ultrasonic;warming)
Smiles
CCC1(C2=CN=CN2)CC3=C(C=CC=C3)C1.[H]Cl
Molecular Weight
248.75
References & Citations
[1]Pertovaara A, et al.Pharmacological properties, central nervous system effects, and potential therapeutic applicationsof atipamezole, a selective alpha2-adrenoceptor antagonist. CNS Drug Rev. 2005 Autumn;11(3):273-88.bioRxiv. 2024 November 03.|Protein Cell. 2019 Mar;10(3):178-195.|Brain Res. 2020 Sep 15;1743:146949.|Eur J Neurosci. 2021 Apr 27.|Exp Mol Pathol. 2021 Feb;118:104587.|Front Cell Dev Biol. 2021 Mar 11;9:636327.|Research Square Preprint. 2022 May.|Sci Transl Med. 2022 Nov 3;eabq4064.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12380/Atipamezole-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12380/Atipamezole-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
104075-48-1
Available Sizes
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