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Enpp-1-IN-5

Enpp-1-IN-5 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) . The ENPP 1 has broad specificity and can cleave a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds nucleotides and nucleotide sugars. Enpp-1-IN-5 has the potential for the research of cancer and infectious diseases (extracted from patent WO2019046778A1/WO2021203772A1, compound 1) [1][2].

Product Specifications

CAS Number

2230916-95-5

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/enpp-1-in-5.html

Purity

98.16

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(N)(NCCC1CCN(CC1)C2=C3C=C(OC)C(OC)=CC3=NC(N)=N2)=O

Molecular Formula

C17H26N6O4S

Molecular Weight

410.49

References & Citations

[1]William Michael Gallatin, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitors and uses thereof. Patent WO2019046778A1.|[2]Bang Fu, et al. Ectonucleotide pyrophosphatase-phosphodiesterase 1 inhibitors, compositions and uses thereof. Patent WO2021203772A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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