Disitamab
Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985) [1].
Product Specifications
CAS Number
[2185868-98-6]
Product Name Alternative
RC48-0
UNSPSC
12352203
Target
ADC Antibody; EGFR
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/disitamab.html
Purity
98.70
Solubility
10 mM in DMSO
Smiles
[Disitamab]
Molecular Weight
(144.16 kDa)
References & Citations
[1]Jiang J, et al. Preclinical safety profile of disitamab vedotin: a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 4
Isoform
ErbB2/HER2
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