Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IL-17A, Human (HEK293, His)

IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases[1][2]. IL-17A Protein, Human (HEK293, His) is a recombinant human IL-17A protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 132 amino acids (G24-A155) .

Product Specifications

Product Name Alternative

IL-17A Protein, Human (HEK293, His), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-17a-protein-human-hek293-his.html

Purity

98.0

Smiles

GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA

Molecular Formula

3605 (Gene_ID) Q16552 (G24-A155) (Accession)

Molecular Weight

Approximately 15-24 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Chen K, et al. Interluekin-17A (IL17A) . Gene. 2017 May 30;614:8-14.|[2]Iwakura Y, et al. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol Rev. 2008 Dec;226:57-79.|[3]Cua DJ, et al. Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol. 2010 Jul;10 (7) :479-89.|[4]Wright JF, et al. The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex. J Immunol. 2008 Aug 15;181 (4) :2799-805.|[5]Kinoshita H, et al. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J Allergy Clin Immunol. 2009 Jan;123 (1) :179-86.|[6]Henness S, et al. IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290 (6) :L1283-90.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PB1 Recombinant Antibody, PE-Cy5 Conjugated
bsm-61815R-PE-Cy5-TR 20 µL

PB1 Recombinant Antibody, PE-Cy5 Conjugated

Sign In for Pricing
View Details
Human CRK ELISA KIT
EF005696 96 Tests

Human CRK ELISA KIT

Sign In for Pricing
View Details
2210411K11Rik Protein Vector (Mouse) (pPM-C-HA)
PV147856 500 ng

2210411K11Rik Protein Vector (Mouse) (pPM-C-HA)

Sign In for Pricing
View Details
Human Selectin, Leukocyte (SELL) Antibody Pair Kit (with Standard)
MBS2098388-01 5x 96 Tests

Human Selectin, Leukocyte (SELL) Antibody Pair Kit (with Standard)

Sign In for Pricing
View Details
Human Selectin, Leukocyte (SELL) Antibody Pair Kit (with Standard)
MBS2098388-02 5x 96 Tests + MBS2090685 (Ab Pairs Support Pack 1,5x 96 Tests)

Human Selectin, Leukocyte (SELL) Antibody Pair Kit (with Standard)

Sign In for Pricing
View Details
Human Selectin, Leukocyte (SELL) Antibody Pair Kit (with Standard)
MBS2098388-03 10x 96 Tests

Human Selectin, Leukocyte (SELL) Antibody Pair Kit (with Standard)

Sign In for Pricing
View Details