Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PBX-7011 (TFA)

PBX-7011 TFA is a derivative of camptothecin (HY-16560), which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity[1].

Product Specifications

UNSPSC

12352005

Target

Bcl-2 Family; Survivin

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pbx-7011-tfa.html

Purity

99.11

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(O)C(F)(F)F.N[C@@H]1C2=C3C(C=C4C(OCO4)=C3CC1)=NC5=C2CN6C5=CC7=C(COC([C@]7(O)CC)=O)C6=O

Molecular Formula

C26H22F3N3O8

Molecular Weight

561.46

References & Citations

[1]Jung DY, et al. Camptothecin derivatives that bind to ddx5 protein and prodrugs thereof. WO2023204631A1. 2023-10-26.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CPT1B Antibody
GWB-MQ462C 50 µg

CPT1B Antibody

Ask
View Details
2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl Trichloroacetimidate
MBS6019774-01 500 mg

2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl Trichloroacetimidate

Ask
View Details
2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl Trichloroacetimidate
MBS6019774-02 5x 500 mg

2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl Trichloroacetimidate

Ask
View Details
E6 (HRP)
561076-01 50 µg

E6 (HRP)

Ask
View Details
E6 (HRP)
561076-02 100 µg

E6 (HRP)

Ask
View Details
RERG Polyclonal Antibody, Cy3 Conjugated
bs-6091R-Cy3 100 µL

RERG Polyclonal Antibody, Cy3 Conjugated

Ask
View Details