4-Isopropylcatechol

4-Isopropylcatechol is a potent and irreversible cutaneous depigmenting agent. 4-Isopropylcatechol significantly inhibits protein biosynthesis in mouse melanoma cells containing high levels of tyrosinase. 4-Isopropylcatechol can be use to study hyperpigmentation of skins[1][2].

Product Specifications

CAS Number

[2138-43-4]

Product Name Alternative

4-IPC

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/4-isopropylcatechol.html

Purity

98.03

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C(C)C)C=C1O

Molecular Formula

C9H12O2

Molecular Weight

152.19

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Sugano H, et al. Tyrosinase-mediated inhibition of in vitro leucine incorporation into mouse melanoma by 4-isopropylcatechol. Cancer Res. 1975 Nov;35 (11 Pt 1) :3126-30.|[2]Bleehen SS. The treatment of hypermelanosis with 4-isopropylcatechol. Br J Dermatol. 1976 Jun;94 (6) :687-94.