4-Isopropylcatechol
4-Isopropylcatechol is a potent and irreversible cutaneous depigmenting agent. 4-Isopropylcatechol significantly inhibits protein biosynthesis in mouse melanoma cells containing high levels of tyrosinase. 4-Isopropylcatechol can be use to study hyperpigmentation of skins[1][2].
Product Specifications
CAS Number
2138-43-4
Product Name Alternative
4-IPC
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/4-isopropylcatechol.html
Purity
98.03
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C(C)C)C=C1O
Molecular Formula
C9H12O2
Molecular Weight
152.19
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Sugano H, et al. Tyrosinase-mediated inhibition of in vitro leucine incorporation into mouse melanoma by 4-isopropylcatechol. Cancer Res. 1975 Nov;35 (11 Pt 1) :3126-30.|[2]Bleehen SS. The treatment of hypermelanosis with 4-isopropylcatechol. Br J Dermatol. 1976 Jun;94 (6) :687-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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