Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PSMα3

PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) [1][2].

Product Specifications

CAS Number

1001405-52-2

UNSPSC

12352209

Target

Toll-like Receptor (TLR)

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/psmα3.html

Purity

98.75

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CC(N)=O)=O)=O)CC(C)C)=O)=O)CCCCN)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)=O)(CC3=CC=CC=C3)NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@H](CCSC)NC=O)=O)CCC(O)=O)=O)=O)C(C)C)=O)C)=O)CCCCN)=O)CC(C)C)=O)=O)CCCCN)=O

Molecular Formula

C128H192N28O30S

Molecular Weight

2635.13

References & Citations

[1]Richardson JR, et, al. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018 Nov 13;9:2603.|[2]Tayeb-Fligelman E, et, al. The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril. Science. 2017 Feb 24;355 (6327) :831-833.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)
MBS2040386-01 0.1 mL

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)

Sign In for Pricing
View Details
FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)
MBS2040386-02 0.2 mL

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)

Sign In for Pricing
View Details
FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)
MBS2040386-03 0.5 mL

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)

Sign In for Pricing
View Details
FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)
MBS2040386-04 1 mL

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)

Sign In for Pricing
View Details
FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)
MBS2040386-05 5 mL

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)

Sign In for Pricing
View Details
FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)
MBS2040386-06 5x 5 mL

FITC-Linked Polyclonal Antibody to Inhibin Binding Protein (INHBP)

Sign In for Pricing
View Details