Urea-15N2

Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

Product Specifications

CAS Number

[2067-80-3]

Product Name Alternative

Carbonyl diamide-15N2

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/urea-15n2.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[15NH2]C([15NH2])=O

Molecular Formula

CH4 15N2O

Molecular Weight

62.04

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100 (9) :5142-7.|[3]Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 15;19 (11) :20392.|[4]Wang H, et al. Urea. Subcell Biochem. 2014;73:7-29.