Acetoacetic acid (sodium)
Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases[1][2][3].
Product Specifications
CAS Number
[623-58-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/acetoacetic-acid-sodium.html
Purity
98.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
CC(CC(O[Na])=O)=O
Molecular Formula
C4H5NaO3
Molecular Weight
124.07
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
CNTN1, ID (CNTN1, Contactin-1, Glycoprotein gp135, Neural cell surface protein F3) (MaxLight 750)
CNTN1, ID (CNTN1, Contactin-1, Glycoprotein gp135, Neural cell surface protein F3) (MaxLight 750)
