PARP1-IN-7
PARP1-IN-7 is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP1) as an anticancer agent.
Product Specifications
CAS Number
2084112-75-2
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp1-in-7.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(N2CCN([C@H]3C=C(C4=CC5=C(C(N4)=O)C=CC=N5)CC3)CC2)C=C1
Molecular Formula
C24H23N5O
Molecular Weight
397.47
References & Citations
[1]Karche NP, et al. Discovery of isoquinolinone and naphthyridinone-based inhibitors of poly (ADP-ribose) polymerase-1 (PARP1) as anticancer agents: Structure activity relationship and preclinical characterization. Bioorg Med Chem. 2020 Dec 15;28 (24) :115819.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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