Tubulin inhibitor 11
Product Specifications
UNSPSC Description
Tubulin inhibitor 11 is a potent and orally active tubulin inhibitor. Tubulin inhibitor 11 targets the Colchicine binding site on tubulin, inhibits tubulin polymerization, promotes mitotic blockade and apoptosis[1].
Target Antigen
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-11.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C(NS(C2=CC=C(C=C2)C)(=O)=O)=C1)C)NCC3=CN=C(C=C3)C
Molecular Weight
409.50
References & Citations
[1]Songwen Lin, et al. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J Med Chem. 2022 Dec 22;65(24):16372-16391.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152156/Tubulin-inhibitor-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152156/Tubulin-inhibitor-11-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2366260-33-3
Available Sizes
Curated Selection
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