6-Formylpterin

6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells[1].

Product Specifications

CAS Number

[712-30-1]

Product Name Alternative

3,3',4,4'-Benzophenonetetracarboxylic acid,Pentacarboxybenzene

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Reactive Oxygen Species (ROS) ; Xanthine Oxidase

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/6-formylpterin.html

Purity

98.0

Solubility

1 M NaOH : 5 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 33.33 mg/mL (ultrasonic; adjust pH to 12 with 1 M NaOH)

Smiles

O=CC1=CN=C2N=C(N)NC(C2=N1)=O

Molecular Formula

C7H5N5O2

Molecular Weight

191.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Arai T, et al. 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation. Free Radic Biol Med. 2001 Feb 1;30 (3) :248-59.